Term Paper for Bl9G 4520You are required to write a term paper of 20 pages length on a researcharticle that has been published in the last 12 months. lt is due Wed., Nov.23 in class and is worth 24% of your course grade.2. The research article is on the effects of a dietary supptement on abiological system, and ultimately on a clinical health claim. You must: a)describe in general terms what the dietary supplement is and the medicalproblem (s) it is supposed to help with (prevent, ameliorate, cure) b)describe the research paper, including key experimental techniques, keyresults and major conclusions c) scientifically evaluate the article and d)draw conclusions about the article relative to the overall literature and therelevant health claim.3. You will work with a partner who has an interest in the sanle dietarysupplement, but will evaluate a differ,ent research article and perhaps adifferent health claim. You will only have to work together on theintioduction [2a, usually about 4 pages], but work independently on yourown research article (12 b, c and d, usually about 8 pages eachl. Youmight find it useful to compare and contrast your 2 articles at the end. Youwill be graded separately, mostly on2 b, c and d.4. Any discussion needs to include analysis at a molecular level(proposed mechanism of action), cellular effects, organ-level effects and.up to the intact organism / human patient.5. Example term-papers will be posted on course-links to guide you.6, You must find a partner and a research article by the last Friday ofSeptember, and each of you must submit a one-page qufline (forfeedback,notgraded).Findatopicyouare@goforit!lntro – Pg.2I eYnd#la1″Term Paper for BIOC*4520A requirement for BlOC.4520 is the completion of a term paper on the topic of dietarysupplements (worth 24o/o of course grade). A dietary supplement is a product intended tosupplement the diet that bears or contains one or more of the following dietary ingredients:a) vitamin, mineral, or amino acid b) herb or other botanical c) dietary substance or d)concentrate, metabolite or combination.Examples of Dietary lngredients (see extensive list below):vitamin, mineral, amino acid:herb or botanical:dietary substance, not yet clearly defined:. Vitamin E, selenium, glutamine. Echinacea. bee pollenThe supplement can be in the form of a concentrate, tablet, constituent or extract.Think of a dietary supplement that interests you, and find a peer-reviewed scientific studypublished in the last 12 months about that compound. The paper should relate to somespecific he?lth claim involving large doses of the compound. Simple addition of a vitaminor mineral to a deficient group (ex, Vitamin C to patients with scurvy) is not a suitable topic,The paper can be at the molecular level (retinoic acid binding to its receptor), cellular,organ, whole experimental animal studies or clinical studies (megadose Vitamin Asupplements given to 10,000 lung cancer patients). Each level has its own advantages /disadvantages. The following search engines should help:http ://d ietary-suppleme,nts. infq. n ih. gov (look for I B I DS search en g ine)http ://www4. ncb i. nlm. n i h. g ov/entrez/q uery.fcqi ( Pub Med)http ://www.scholar. o oog le. com .Your task is to decide on a supplement you are interested in and fin a partner who is alsointerested in this supplement. The two of you should collaborate to discuss the basicbiochemistry / chemistry of the supplement (figures, structures and pathways areencouraged), discuss the research study methods, results, interpretations and conclusionsin a thoughtful, critical (good and bad) manner. Your term paper should be no more than 20paoes double spacqd (not including figures, references, etc.). A one-page outline and acopy of your paper is due the lpqt Friday of Sept. lt will not be graded, and you will get 1%on your course grade for handing it in on time. The purpose of the outline is to ensure youhave picked an suitable paper and are on the right track before you invest a lot of work inyour paper.A word about the nasty subject of plasiarism – don’t do it! Please see the link:http:4www.webapps.ccs.uoqVelph.cail-clAgademiclntegritv/plagiadsm.cfmRandom Google searches of your papers will be done. lf you copy word-for-word from theliterature, you risk being expelled from the university for plagiarism! The journal “Nature”suggests that six words used contiguously from another person’s work can constituteplagiarism (Nature 435,258-9; 2005). Read carefully and widely, but write down key pointsin your own words and craft your own argument.lntro – Pg. 3Tips on Term Paper
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