Describe the pathophysiology of PDA and why the history of PDA is significant in this scenario.

Describe the pathophysiology of PDA and why the history of PDA is significant in this scenario.


Patent ductus arteriosus (PDA) is a congenital heart defect that has been present in the medical literature since the 1700s. This essay will explore the pathophysiology of PDA, its historical significance, and its current clinical implications. To begin, an overview of the pathophysiology of PDA will be discussed and followed by an examination of the historical significance of PDA. Finally, the clinical implications of PDA in the present day will be discussed.
Patent ductus arteriosus (PDA) is a congenital heart defect in which the ductus arteriosus in the fetal heart fails to close after birth, leaving an abnormal connection between the pulmonary artery and the aorta (Dice & Bhatia, 2007). This connection allows for the continuous flow of oxygenated and unoxygenated blood from the pulmonary artery to the aorta, resulting in a decrease in cardiac output and an increase in pulmonary blood flow. The increased pressure in the pulmonary artery can lead to pulmonary overcirculation, resulting in pulmonary hypertension and left-sided heart failure. PDA is commonly seen in premature infants, but can also affect full-term babies. The pathophysiology of PDA is complex and is thought to involve genetic, environmental, and hormonal factors (Dice & Bhatia, 2007). The exact cause of PDA is unknown, but it is believed to be associated with an imbalance between the production and breakdown of certain factors that regulate the tone of the ductus arteriosus, such as prostaglandins and nitric oxide. Other risk factors for PDA include maternal diabetes, maternal hypertension, intrauterine infection, and exposure to certain medications or drugs. Diagnosis of PDA is usually made through echocardiography or other imaging techniques, and treatment is typically medical or surgical. In conclusion, PDA is a complex congenital heart defect that can have serious consequences if left untreated. (Dice & Bhatia, 2007).
The study published in the Journal of Veterinary Internal Medicine in 2014 by AB Saunders et al. aimed to examine the historical significance of Patent Ductus Arteriosus (PDA). This anomaly is a common congenital defect in dogs and cats, and has been described in the medical literature since the mid-19th century. The study found that the development of treatments to remedy the condition has been gradual and has significantly evolved over time. Initially, the main interventions used to treat PDA were surgical ligation and thoracic duct ligation. However, with the development of new technologies, minimally invasive therapies have become the preferred option for treatment. The authors concluded that the current therapeutic strategies for PDA can be attributed to the gradual development of treatments over time and that the historical significance of PDA should not be ignored.
In present day, there is a growing awareness of the clinical implications of patent ductus arteriosus (PDA). In a study conducted by Kang et al. in 2014, the authors observed that PDA, which is a common congenital heart defect, may lead to an increased risk of pulmonary hypertension and other pulmonary complications. These findings have been supported by other studies indicating that, in some cases, PDA can cause heart failure and other cardiovascular problems. Furthermore, Kang et al. concluded that the risk of mortality associated with PDA is significantly higher than in the general population. As a result, it is important for clinicians to be aware of the potential implications of PDA in order to provide the best possible care to their patients. Additionally, Kang et al. suggested that early diagnosis and treatment of PDA can be beneficial in reducing the risk of further complications and mortality associated with the condition. In conclusion, it is clear that PDA has serious clinical implications and that it is important for clinicians to be aware of the potential risks associated with the condition. (Kang, Wang, Axell-House, Soni, et al., 2014).
PDA, or patent ductus arteriosus, is a congenital heart defect in which a blood vessel, the ductus arteriosus, fails to close following the birth of a baby. This can be triggered when the ductus arteriosus fails to close or re-open after the delivery. PDA is a significant medical condition, as it can lead to complications such as heart failure and stroke. The history of PDA is important, as it has been understood since the 1500s, when it was first described by Anatomist, Andreas Vesalius and studies of the pathophysiology of PDA have continued to this day. Awareness of the pathophysiology of PDA is essential for successful treatment.
Work Cited
P Soni.”Clinical significance of serum COL6A3 in pancreatic ductal adenocarcinoma.”
AB Saunders., SG Gordon.”Long‐term outcome in dogs with patent ductus arteriosus: 520 cases (1994–2009).”
“Patent ductus arteriosus: an overview.”



Get Assignment Help- Confidentially!

Why Choose Ace Writing Center?

***Absolutely NO Plagiarism.

***All writing is original.

***Guaranteed Top Grade.

***24/7 Support

***100% Money Back Guarantee

***Free revision



Get 20% Discount on This Paper
Pages (550 words)
Approximate price: -

Try it now!

Get 20% Discount on This Paper

We'll send you the first draft for approval by at
Total price:

How it works?

Follow these simple steps to get your paper done

Place your order

Fill in the order form and provide all details of your assignment.

Proceed with the payment

Choose the payment system that suits you most.

Receive the final file

Once your paper is ready, we will email it to you.

Our Services

Ace Writing Center has stood as the world’s leading custom essay writing services providers. Once you enter all the details in the order form under the place order button, the rest is up to us.


Essay Writing Services

At Ace Writing Center, Nowadays, students normally have extremely busy schedules. You will note that some of them have to take on some evening or weekend jobs in order to get some income that can help them to sustain in college or in the university. This can deny them a chance to write all the essays given. Others usually get bombarded with a lot of work by their lecturers. This can still delay such students from working on all their essays. However, some of them usually try to work on all these essays but end up delivering their work late. This can prevent them from graduating since most lecturers are strict on deadlines. If you want to write a business essay, the wise way is to hire an outstanding essay writing service like us, so that you can get the best results. If you are keen, you will note that many companies usually overcharge their customers. Some of them are there only to make money. And in reality, they really don’t care to build a long term commitment with students. You should not choose such companies. You should take your time and choose a reliable company to work with. Ace Writing Center is the ultimate solution for you. We have been offering our writing service for more than 7 years. This is a clear indication that you will get quality essay writing service. We have a wide range of writers who can work on any business essay that you might have. We believe in doing extensive research so that we can provide quality work to all our clients. .


Admission and Business Papers

Have you ever had to write an admission essay for college? The majority of students face the same issues when applying to a university or college and many in such situations decide they need professional help to cope with this matter. They get in a situation when the deadline keeps coming closer but lack motivation to start because they are just not sure if their writing skills are strong enough. We have a solution for you! Ace Writing Center is the best admission essay writing service with a large professional team and years of experience in providing high-quality papers to students of all levels and faculties. The mission of our team is to help students make their dreams of entering a good college come true and that’s what we offer!.


Editing and Proofreading

Sometimes all the words for your paper just flow out of your mind and into your fingers. You type quickly at your keyboard and there they are, your beautiful words right there on the screen. But you have no idea how to polish it up. You may be wishing there was a paper writing service that offered this type of writing service. Look no more! Here at Ace Writing Center, we offer you an editing and proofreading option that you can't find anywhere else..


College Essay Writing

In case you are familiar Ace Writing Center, you know the way to distinguish a better company from a cheap one exactly. First of all, poor service website does not have a sufficient support. We think support team is an essential part of success; it has to answer all clients’ questions and be a connecting link between clients and their writers. On our web-service you will get answers about anything you need and your writer will receive all your instructions, assignments and requirements exactly and swiftly. A writing service that we run has got a flexible pricing system that will save you from senseless wastes and many bonus systems that let you sparing money for something important for you.

Open chat
Hello. Can we help you?